EDTA is a synthetic amino acid and chelating agent that binds to metal ions, forming stable complexes. This binding process alters the metal’s reactivity and allows for removal. It is commonly used by health professionals in chelation therapy to target unwanted heavy metals like lead, cadmium, arsenic, and mercury in the body.

Why Calcium Disodium EDTA?

Calcium disodium EDTA is the preferred form due to its selective chelation of toxic heavy metals while sparing essential minerals, and because of its established safety and common use by health professionals.

How does EDTA work as a chelating agent?

EDTA binds to metal ions, surrounding them in a stable structure. This process alters their chemical reactivity and allows for their removal.

What metals do EDTA (calcium disodium EDTA) bind to?

It can bind to a wide range of metals but binds most aggressively with lead, mercury, aluminum, and cadmium.

How should I take EDTA for maximum efficacy?

For best results, take EDTA on an empty stomach. This prevents EDTA from binding to minerals in food and ensures optimal interaction with unwanted metals.

Can I take all my EDTA capsules for the day at once, or do they need to be spread out?

Yes, you can take all your EDTA capsules at once. It is easier and more effective to take them on an empty stomach.

How many EDTA capsules should I take each day?

We recommend taking 1-3 capsules daily, which provides 600-1800mg of calcium disodium EDTA per day.

Does calcium disodium EDTA remove calcium from the body?

Calcium disodium EDTA does not aggressively bind to calcium. It is pre-bound to calcium, making it selective for other metal ions.

Does calcium disodium EDTA pass the blood-brain barrier?

No, calcium disodium EDTA does not significantly cross the blood-brain barrier.

Can I take EDTA continuously, or should I cycle on and off?

It is recommended to cycle EDTA usage, such as 6 weeks on and 2 weeks off, to maintain a healthy balance of essential minerals.

Do I need to take a multi-mineral supplement while taking EDTA?

Yes, it is a good idea to take a daily multi-mineral supplement at a different time from EDTA to help replenish essential minerals.

What are Arizona Natural EDTA capsules made of?

Arizona Natural EDTA capsules are made of bovine gelatin.

Are your EDTA capsules kosher?

Yes, our EDTA capsules are kosher.

Are your EDTA capsules halal?

Yes, our EDTA capsules are halal.

Is Arizona Natural EDTA made in the USA and third-party tested?

Yes, our EDTA is made in the USA and undergoes third-party testing in certified U.S. laboratories. All manufacturing is done in certified GMP facilities.

Natural Seasonal Relief - Cold, Flu, Allergies

Cold & Flu Formula - 13 Natural Ingredients

Cold & Flu Formula - 13 Natural Ingredients

Regular price $17.39 USD

Regular price Sale price $17.39 USD
Unit price per
Arizona Natural Allergy Formula - Seasonal Wellness Support

Arizona Natural Allergy Formula - Seasonal Wellness Support

Regular price $17.49 USD

Regular price Sale price $17.49 USD
Unit price per

News and Product Info

View all

Why Arizona Natural Cold & Flu Formula?

June 2, 2026
Arizona Natural Cold and Flu Formula combines 13 carefully selected botanicals and nutrients, including Traditional Chinese Medicine herbs, Vitamin C, and Zinc

Why Arizona Natural Cold & Flu Formula?

June 2, 2026
Arizona Natural Cold and Flu Formula combines 13 carefully selected botanicals and nutrients, including Traditional Chinese Medicine herbs, Vitamin C, and Zinc
Yucca Root: A Traditional Desert Botanical for ...

May 28, 2026
Yucca schidigera is native to the dry regions of the American Southwest and northwestern Mexico and has been valued for generations as a source of fiber, natural cleansing compounds, and...

Yucca Root: A Traditional Desert Botanical for ...

May 28, 2026
Yucca schidigera is native to the dry regions of the American Southwest and northwestern Mexico and has been valued for generations as a source of fiber, natural cleansing compounds, and...
Comparing 2 Types of Garlic - Cultivated Garlic...

May 21, 2026
Here we compare two of the most popular and therapeutically active Garlics, Allium sativum, the typical cultivated garlic and Allium ursinum, a wild European garlic known as Wild Bear's Garlic.

Comparing 2 Types of Garlic - Cultivated Garlic...

May 21, 2026
Here we compare two of the most popular and therapeutically active Garlics, Allium sativum, the typical cultivated garlic and Allium ursinum, a wild European garlic known as Wild Bear's Garlic.